We have reached the end of the first quarter of 2021, which is an important date for analyzing the evolution of the Spanish vaccination process. In this chartbook we explain briefly and concisely weather the government’s vaccionation objectives have been achieved in the first quarter of the year and what the foreseeable evolution will be in the coming months. Since Spain is beginning to reach high vaccination rates in certain social groups, we have decided to analyze the impact of the vaccine on them and thus observe whether we can already appreciate the positive impact of vaccines, revalidating, or not, the results obtained in countries more advanced in the vaccination process such as the United Kingdom or Israel. We also analyze the health situation, both nationally and internationally, together with its foreseeable evolution in the coming days.